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Accelerating Antibody Discovery with Precision

DIMA Biotechnology delivers cutting-edge monoclonal antibodies, membrane proteins, and advanced development platforms to empower biopharma innovation from target validation to clinical candidates.

About DIMA Biotechnology

A leading biotech company dedicated to accelerating antibody-based drug discovery through innovative platforms and a vast portfolio of pre-validated molecules.

DIMA Biotechnology LLC is a top-tier provider of preclinical research and development solutions for the global biopharmaceutical industry. We specialize in delivering high-quality, pre-designed, and validated antibody molecules tailored for early-stage drug development.

Our extensive portfolio includes over 5,000 readily available lead antibody molecules targeting approximately 400 unique drug targets. Each molecule comes with verified sequences and comprehensive validation data, enabling rapid progression in therapeutic discovery.

With a mission to empower BioPharma innovation, we combine cutting-edge technology with flexible partnership models to expedite the development of life-changing therapies.

5,000+
Lead mAbs Available
400+
Drug Targets Covered
1,000+
Functional Proteins
48 Days
Avg. Engineering Turnaround

Our Core Values

I

INTEGRITY

P

PRAGMATISM

I

INNOVATION

F

FOCUS

Innovative Technology Platforms

Our proprietary platforms enable faster, more efficient antibody discovery, engineering, and evaluation.

DiMPro™ Membrane Protein Platform

DiMPro Platform

Utilizes HEK293 mammalian expression system to produce functional membrane proteins with authentic post-translational modifications. Offers five solutions: MNP, VLP, EXO, Detergent, and Synthetic Nanodisc.

  • • 500+ active full-length multi-pass proteins
  • • High solubility & correct folding
  • • Ideal for GPCRs, ion channels

Single B Cell mAb Platform

Single B Cell Platform

Direct isolation of positive B cells from immunized animals eliminates hybridoma fusion. Enables sequencing of over 1,000 positive clones per animal with higher hit rates.

  • • No hybridoma required
  • • 10,000+ hits in one month
  • • High positive clone rate

DiLibrary™ Mammalian Display

DiLibrary Platform

One-step antibody engineering platform for humanization, chimerization, and affinity maturation. Delivers results in 48 days with superior developability.

  • • 48-day turnaround
  • • $20K–$40K cost range
  • • High affinity retention

DiAssay™ Evaluation Platform

DiAssay Platform

Comprehensive screening for optimal hit molecules across multiple modalities: Bispecifics, ADCs, and CAR-T therapies.

  • • Bispecific Antibody screening
  • • ADC internalization assays
  • • CAR-T functional evaluation

Functional TP Development

Focuses on transmembrane protein expression and functional characterization using mammalian systems for high biological relevance.

  • • Full-length protein production
  • • Activity-confirmed batches
  • • SPR-ready formats

DiNabody™ Nanobody Discovery

Advanced nanobody discovery service using camelid immunization and high-throughput screening for small, stable, high-affinity binders.

  • • High thermal stability
  • • Deep tissue penetration
  • • Ideal for diagnostics & imaging

Our Product Portfolio

From membrane proteins to biosimilar antibodies, we offer a comprehensive suite of research tools for drug discovery.

CD40 ELISA Antibody

Anti-CD40 mAb (DME100102)

ELISA-validated monoclonal antibody for immune checkpoint research.

Cat#: DME100102 | Reactivity: Human | Application: ELISA, WB
CD47 Protein

CD47 ECD Protein (PME100008)

Recombinant human CD47 extracellular domain for binding studies.

Cat#: PME100008 | Tag: His | Purity: >95%
FCRL5 Antibody

Anti-FCRL5 mAb (DME100853)

IHC-validated antibody for B-cell malignancy research.

Cat#: DME100853 | Application: IHC, Flow Cytometry
Canine IL-31 ELISA

Canine IL-31 ELISA Kit

Quantitative detection of canine interleukin-31 in serum.

Cat#: DME101126 | Sensitivity: 15 pg/mL
Anti-His mAb

Anti-His Monoclonal Antibody

High-affinity tag antibody for protein detection and purification.

Clone: H10 | Application: WB, IP, ELISA
Synthetic Nanodisc

Synthetic Nanodisc Protein

Stable membrane protein in lipid bilayer for structural studies.

Size: 10–12 nm | Compatible with SPR, Cryo-EM
Biosimilar Reference Antibody

Biosimilar Reference mAb

Reference standards for biosimilar development and QC testing.

Over 1,400 available | Sequence-verified
ADC Internalization Assay Kit

ADC Internalization Assay Kit

Fluorescence-based kit to evaluate ADC uptake in target cells.

Excitation: 488 nm | Compatible with HTS

Comprehensive Research Services

From custom protein expression to antibody engineering, we support your discovery pipeline at every stage.

Custom Protein Services

  • • Custom ECD Protein Service
  • • Full-length Membrane Protein Expression
  • • Tag-Free Recombinant Protein Production
  • • SPR Binding Assay Service
  • • Overexpression Stable Cell Line Generation

Custom Antibody Services

  • • Rabbit & Mouse Monoclonal Antibody Development
  • • DiNabody™ Nanobody Discovery
  • • Antibody Humanization & Affinity Maturation
  • • CAR-T Target Evaluation
  • • Lead Antibody Molecule Licensing (5,000+ available)
1,746
ECD Proteins
1,492
Full-Length Transmembrane Proteins
1,113
Monoclonal Antibodies
1,424
Biosimilar Reference Antibodies

Frequently Asked Questions

What is DIMA’s lead mAb out-licensing program?

We offer over 5,000 pre-sequenced lead monoclonal antibodies for immediate licensing, covering ~400 drug targets with full validation data.

Can you customize membrane protein expression?

Yes, we provide custom full-length membrane protein services using mammalian (HEK293) systems with multiple stabilization options.

How fast is antibody humanization via DiLibrary™?

Our mammalian display platform delivers engineered antibodies in just 48 days with high humanization and affinity retention.

Do you offer ADC development support?

Yes, we provide anti-payload antibodies and internalization assay kits to support ADC development and evaluation.

Get in Touch

Contact DIMA Biotechnology for product inquiries, collaborations, or technical support.

Phone (USA): +1 9789120878
Phone (China): +86-18062749453
Email: info@dimabio.com / orders@dimabio.com
Address: Wuhan Institute of Biotechnology B7, Biolake No.666 Gaoxin Road, Wuhan, Hubei, China 430074

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