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The Predictive Precision of Laser Force Cytology™ for Advanced Biomanufacturing

LumaCyte’s label-free single-cell analysis platform, Radiance®, utilizes Laser Force Cytology™ to deliver advanced analytics for real-time bioprocess monitoring and quality control—reshaping the world of bioanalytics, one cell at a time.

Explore Radiance®
Radiance Instrument

Revolutionizing Cell Analysis with Laser Force Cytology™

LumaCyte’s Laser Force Cytology™ detects subtle phenotypic changes in cells, rapidly measuring quantitative early indicators of cellular response—without the need for antibody or genetic labeling. This breakthrough enables real-time, label-free single-cell analysis for advanced biomanufacturing and research.

What is Laser Force Cytology™?

Laser Force Cytology™ (LFC™) measures optical and fluidic forces within a microfluidic channel to quantitatively characterize innate cellular responses based purely on intrinsic biophysical and biochemical properties. This allows for label-free, real-time analysis of single cells with unparalleled sensitivity.

  • ✅ No labeling required – preserves cell viability
  • ✅ Real-time Process Analytical Technology (PAT)
  • ✅ Detects subtle phenotypic changes early
  • ✅ Applicable across virology, gene therapy, and biomanufacturing
Laser Force Cytology Diagram

Advanced Single Cell Analysis Products

LumaCyte’s Radiance® platform delivers label-free, real-time microfluidic cell analysis—empowering researchers with deep, single-cell insights across bioprocessing, therapy development, and discovery.

Radiance Instrument

Radiance®

Label-free, real-time microfluidic cell analyzer that measures optical force to characterize individual cells with high precision.

  • • No labeling required
  • • Real-time bioprocess monitoring
  • • High-throughput single-cell analysis
  • • Compatible with diverse cell types
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Illuminate Software

Illuminate™

Radiance® single-cell analysis software for real-time data visualization, analysis, and reporting.

  • • Real-time data streaming
  • • Intuitive user interface
  • • Advanced analytics dashboard
  • • Seamless instrument integration
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ReportR Software

ReportR™

Cloud-based SaaS platform for cell analysis, enabling rapid data visualization, trend analysis, and report generation.

  • • Web-based access
  • • Customizable analysis workflows
  • • Collaborative data sharing
  • • Secure cloud storage
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Analyzer Module

Analyzer

Core detection module that measures optical forces and fluid dynamics within the microfluidic channel.

  • • High-sensitivity photodetectors
  • • Real-time force calibration
  • • Low-noise signal processing
  • • Automated alignment
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Sampler Module

Sampler

Automated sample handling system for consistent, high-throughput cell delivery to the analyzer.

  • • 96-well plate compatibility
  • • Precise volume control
  • • Temperature-regulated storage
  • • Barcode scanning
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Multivariate Analysis Tools

Multivariate Analysis

Advanced statistical tools to extract meaningful patterns from complex single-cell datasets.

  • • PCA and clustering algorithms
  • • Dynamic response modeling
  • • Anomaly detection
  • • Batch-to-batch comparison
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Laser Module

LFC™ Core

Precision laser system enabling non-contact optical force measurement at the single-cell level.

  • • Tunable laser wavelengths
  • • Sub-micron beam focus
  • • Low phototoxicity
  • • Long-term stability
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Service & Support

LumaCyte Services

Comprehensive support including installation, training, maintenance, and application development.

  • • On-site and remote support
  • • Custom assay development
  • • Regulatory documentation
  • • 24/7 technical assistance
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Broad Applicability Across Advanced Therapies

LumaCyte’s label-free platform enables real-time monitoring and quality control across a wide range of applications in biomanufacturing, therapy development, and infectious disease research.

Vaccines

Rapid viral infectivity measurements for vaccine development and manufacturing.

Cell Therapy

Cell health, activation, and transduction analytics for CAR T-cell and other immunotherapies.

Gene Therapy

Transfection efficiency and cell response monitoring in gene delivery workflows.

Biomanufacturing & PAT

Real-time process analytical technology for bioprocess monitoring and QC.

iPSC Differentiation

Label-free tracking of stem cell differentiation dynamics.

Adventitious Agent Testing (AAT)

Early detection of contamination in bioproduction environments.

Infectious Disease

Host-pathogen interaction studies and antiviral screening.

Pre-Clinical Drug Discovery

High-content screening of cellular responses to novel therapeutics.

Cloud-Powered Data Intelligence

ReportR™ is LumaCyte’s cloud-based cell analysis software platform—designed from the ground up to streamline data analysis, visualization, and reporting.

  • 📊 Intuitive plots and histograms for rapid trend identification
  • ⚡ Accelerates development of custom methods (e.g., viral infectivity assays)
  • 🔐 Secure, scalable, and accessible from anywhere
  • 🔄 Real-time collaboration across teams and sites
Access ReportR™ Portal
ReportR Dashboard

About LumaCyte

LumaCyte, Inc. is an advanced research and bioanalytics instrumentation company pioneering label-free, single-cell analysis. Our mission is to transform biomanufacturing and life science research through the power of Laser Force Cytology™.

By measuring the intrinsic biophysical and biochemical properties of cells—without labels—LumaCyte enables scientists to detect subtle phenotypic changes in real time. This predictive precision supports faster development cycles, improved quality control, and deeper biological insights across gene therapy, cell therapy, vaccine production, and beyond.

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Ready to transform your bioprocess with label-free single-cell analytics?

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