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Nanotechnology Transforming Drug Delivery

nStrada is a subcutaneous implant that provides long-term, constant release of a wide range of drugs and biologics.

Nanochannel Technology Animation

About Us

NanoMedical Systems develops novel drug-delivery devices based on its proprietary nStrada™ nanofluidics platform for sustained release of chronic therapies.

NanoMedical Systems Lab

Our nStrada™ devices can be loaded with a variety of drugs including small molecules, peptides, and proteins for subcutaneous implantation. The devices rely on diffusion (passive or controlled) to achieve steady-state drug concentrations within a few days and then maintain constant release for the duration of the implant.

This performance represents a significant improvement over polymer-based implants and depots, which suffer from an initial burst release and require multiple weeks to achieve steady-state concentrations.

  • Proprietary nStrada™ nanofluidics platform
  • Suitable for small molecules, peptides, and proteins
  • Long-term duration – weeks to over 1 year
  • High reliability and reproducibility (ISO 9001)

nStrada Drug Delivery Platform

Utilizing state-of-the-art semiconductor manufacturing methods and biocompatible materials.

No Power or Moving Parts

Passive diffusion enables long-term constant delivery without external power sources or mechanical components.

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Precision Nanochannels

High-density array of atomic-level precise nanochannels regulates drug molecule outflow with unmatched accuracy.

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No Burst Effect

Achieves steady-state concentrations quickly without the initial burst release common in polymer-based systems.

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Refillable In-Vivo

Gen 2 system allows for in-body refilling during routine office procedures, extending treatment duration.

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Remote Control (Gen 3)

Active control system enables tunable release profiles via remote activation for dynamic therapy management.

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Scalable Manufacturing

Built using leading-edge chip fabrication processes, enabling high-yield, reproducible production.

Nanochannel Chip Concept

Dosing level is set by the number of nanochannels—up to 20 million per cm². Built on leading-edge chip equipment with high-yield processes.

  • • Over 22 patents (US, EU, Canada, China)
  • • Proprietary materials for atomic-level in-body stability beyond 1 year
  • • Smallest bio-robust, dense array nanochannels ever made
  • • Direct scalability to high-volume manufacturing
Nanochannel Chip Diagram

nStrada Platform – Three Delivery Systems

Gen 1: Passive System

  • • Constant release
  • • Low dose volume / longer drug stability
  • • Tested in vitro & in vivo (rodent, dog, pig)

Gen 2: Passive, Refillable

  • • Constant release
  • • Higher doses / shorter drug stability
  • • Tested in vitro & in vivo (non-human primates, pig)

Gen 3: Active Control

  • • Remote control capability
  • • Tunable release
  • • Tested in vitro & in vivo (rodent)

Our Product Platform

The nStrada™ platform supports a wide range of therapeutic applications through customizable delivery systems.

nStrada Implant

nStrada™ Implant (Gen 1)

Passive subcutaneous implant for long-term constant drug release. Ideal for chronic therapies requiring stable pharmacokinetics.

  • • Duration: Weeks to months
  • • Dose Control: Nanochannel density
  • • Status: In vivo tested
Refillable Capsule

Refillable Capsule (Gen 2)

Next-generation system allowing in-body refilling during office visits, reducing implant frequency.

  • • Refillable in vivo
  • • Suitable for higher-dose drugs
  • • Tested in primates and pigs
Active Control Device

Active Control Device (Gen 3)

Remotely programmable implant enabling tunable release profiles for dynamic treatment regimens.

  • • Wireless control
  • • On-demand dosing
  • • In vitro & rodent tested
Nanochannel Chip

nCHP Nanochannel Chip

Core technology component fabricated using semiconductor processes. Up to 20 million channels/cm².

  • • Atomic-level precision
  • • Biocompatible materials
  • • ISO 9001 manufacturing
Lab Research

Therapeutic Development

Platform validated with over 20 drugs (180–149,000 Da). Applicable to small molecules, peptides, and proteins.

  • • Broad API compatibility
  • • High or low solubility
  • • In vitro & in vivo success
Chip Testing

Preclinical Validation

Over 10 animal studies across rat, mouse, dog, and monkey models demonstrating consistent performance.

  • • Multiple species tested
  • • Chronic disease models
  • • Long-term stability data
Custom Implants

Customizable Form Factors

Capsule size and shape tailored independently of dosing parameters for optimal patient fit and comfort.

  • • Flexible design
  • • Subcutaneous placement
  • • Patient-specific options
Combination Product

Combination Product Pathway

Regulatory strategy aligned with FDA combination product guidelines for accelerated development.

  • • Defined regulatory path
  • • Device + drug synergy
  • • Global patent portfolio
Remote Monitoring

Smart Delivery Systems

Future integration with digital health platforms for remote monitoring and treatment optimization.

  • • IoT connectivity
  • • Data-driven dosing
  • • Patient adherence tracking
Scalable Manufacturing

nDS Manufacturing

nStrada devices manufactured in leading-edge chip factories ensuring high reliability and reproducibility.

  • • Semiconductor-grade
  • • High-yield processes
  • • Scalable to volume
Research Collaboration

Partnership Opportunities

Collaborate with us to develop novel delivery solutions for your therapeutic compounds.

  • • Co-development programs
  • • Licensing opportunities
  • • Joint research initiatives
Stability Testing

Long-Term Stability

Proprietary materials and nanostructures provide in-body stability beyond one year.

  • • Atomic-level coatings
  • • Corrosion-resistant
  • • Sustained performance

Competitive Advantage

How nStrada compares to existing drug delivery technologies

Feature nStrada Medici MicroChips Polymers/Depots
Moving Parts No Yes Yes No
Technology Age Cutting-edge 25-year-old Established Mature
Delivery Type Continuous Continuous Dosed Burst + Slow
Form Factor Flexible Single Single Variable
Refillable In-Vivo Yes (Gen 2) No No No
Burst Effect No Minimal No Yes
20+
Drugs Tested In Vitro
10+
Animal Studies
22+
Patents Worldwide
1+
Year In-Body Stability

Frequently Asked Questions

What is the nStrada™ platform?

nStrada is a subcutaneous implant that uses nanofluidics to provide long-term, constant release of drugs and biologics without burst effects.

How does the nanochannel technology work?

The device contains a high-density array of precision nanochannels that regulate drug outflow via passive diffusion, tailored to molecule size and dose rate.

What types of drugs can it deliver?

The platform supports small molecules, peptides, and proteins (180–149,000 Da), with flexibility for high or low solubility compounds.

Is the implant refillable?

Yes, the Gen 2 system is designed to be refillable in vivo during routine office procedures, extending treatment duration.

How long can it deliver drugs?

The system is capable of delivering therapeutics for durations ranging from weeks to over one year, depending on formulation and dose.

Where is it manufactured?

nStrada devices are manufactured in leading-edge semiconductor fabs using ISO 9001 processes, ensuring high reliability and scalability.

Get In Touch

For more information about our technology, partnerships, or investment opportunities, visit our official website.

Visit Official Website

Our Office

NanoMedical Systems, Inc.

HighFlex Technology Center

12708 Riata Vista Circle, Suite A-105

Austin, TX 78727

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