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For over 50 years, Applied Photophysics has delivered precision spectroscopy solutions for cutting-edge research and biopharmaceutical development.
Explore Our ProductsNicoya Acquires Applied Photophysics – Expanding biologics characterization capabilities for faster time-to-clinic and reduced late-stage failures.
Applied Photophysics of Leatherhead, Surrey, UK, is a leading provider of solutions for the biophysical characterisation of biomolecules. With over five decades of innovation, we have been at the forefront of spectroscopy for life science research.
Our Chirascan™ systems use circular dichroism (CD) to characterise changes in the higher-order structure of proteins—critical for innovator drugs and biosimilars. The SX range of stopped-flow spectrometers is the global gold standard for kinetic studies of fast biochemical reactions.
Through a joint venture with Fluorescence Innovations Inc., operating as Protein Stable, we offer high-throughput protein stability screening with microplate-based intrinsic fluorescence thermal ramping and chemical melt plate readers.
Discover the instruments trusted by thousands of researchers and biopharma professionals worldwide.
High-performance circular dichroism spectrometers for protein secondary and tertiary structure analysis. Ideal for biosimilar development and conformational stability studies.
The gold standard for rapid kinetic measurements. Capture millisecond-scale biochemical reactions with unmatched precision and reproducibility.
Label-free, microvolume protein stability screening using intrinsic fluorescence. High-throughput thermal and chemical denaturation analysis.
Advanced CD spectrometer with extended wavelength range and enhanced sensitivity for detailed structural analysis of proteins and nucleic acids.
Versatile kinetic platform for studying enzyme mechanisms, protein folding, and ligand binding with multi-mixing and sequential injection capabilities.
Automated platforms for high-throughput stability profiling of proteins and AAVs. Ideal for formulation development and gene therapy programs.
Compact CD spectrometer designed for routine analysis and QC environments. Offers excellent performance with minimal footprint.
High-end stopped-flow system for advanced kinetic research. Features precision syringes, low noise detection, and modular configuration.
Study protein folding, secondary structure changes, ligand binding, and conformational stability in response to pH, temperature, or denaturants.
Investigate fast enzyme kinetics, protein folding dynamics, electron transfer, and transient intermediate formation in real time.
Perform high-throughput protein stability screening, formulation optimization, and AAV serotype characterisation for gene therapy.
Access user manuals, software downloads, and application notes for all instruments.
Comprehensive maintenance and support packages tailored to your needs.
Enhance your system with the latest detectors, automation, or software features.
On-site or remote training for operators and advanced users.
CD spectroscopy measures differences in the absorption of left and right circularly polarized light. It is used to study the secondary and tertiary structure of proteins and nucleic acids.
Stopped-flow rapidly mixes small volumes of reactants and stops the flow abruptly, allowing the observation of fast reactions on millisecond timescales using various detection methods.
nano-DSF requires no dyes or labels, uses minimal sample volume (2–10 µL), and enables high-throughput screening of protein stability under various conditions.
Yes, Applied Photophysics has service engineers and distributors in over 40 countries, including direct offices in the UK, US, and China.
Have questions about our products or services? Visit our official website to contact the team.
Email: Sales@Photophysics.Com
Phone: +44 1372 386 537 (UK), +1 978 473 7477 (US)
Email: Support@Photophysics.Com
Phone: +44 1372 386 537
Applied Photophysics Limited
21 Mole Business Park
Leatherhead, Surrey KT22 7BA
United Kingdom
Applied Photophysics Inc
2331 Crownpoint Executive Drive, Suite F
Charlotte, NC 28227, USA
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