Our Core Product Lines
Pukang specializes in high-purity intermediates and functional building blocks for peptide therapeutics, ADCs, PROTACs, RNAi, and advanced drug delivery systems.
Semaglutide Intermediates
High-purity side chain and modified amino acids for GLP-1 analog synthesis. Used in diabetes and obesity therapeutics.
- • C18 Fatty Diacid Derivative
- • Aib8-Glu Side Chain
- • Purity: ≥98% (HPLC)
- • Scale: mg to kg
Insulin Degludec Intermediates
Specialized side chain for ultra-long-acting insulin analogs. Critical for basal insulin formulations.
- • C16 Glutamic Acid Derivative
- • Diacid Spacer with Lysine
- • ≥98.5% Purity
- • GMP & R&D Grade
Tirzepatide Intermediates
Dual GIP/GLP-1 receptor agonist building blocks. Includes fatty acid spacers and modified residues.
- • C20 Dicarboxylic Acid
- • Aib3-Glu Side Chain
- • Custom Modifications
- • Scalable Synthesis
Liraglutide Intermediates
C16 fatty acid-modified glutamic acid derivatives for GLP-1 analogs. Used in weight management and diabetes.
- • Palmitoyl-Glu-OH
- • Boc-Protected Forms
- • ≥99% Purity
- • Analytical Support
PEG Reagents
Functionalized PEGs for bioconjugation, solubility enhancement, and half-life extension in biologics.
- • Fmoc-PEG, Boc-PEG, Cbz-PEG
- • MAL-dPEG, DOTA-PEG
- • Click Chemistry PEGs
- • MW: 200–10,000 Da
Advanced Linkers
Precision linkers for ADC, PDC, PROTAC, and RDC platforms. Cleavable and non-cleavable options.
- • Val-Cit, Phe-Lys
- • DBCO, Tetrazine
- • Disulfide & Hydrazine
- • High Stability
API & Advanced Excipients
SNAC, Baricitinib, Eptifibatide, and dipeptides for oral peptide delivery and small molecule APIs.
- • SNAC (Sodium Caprate)
- • Pseudoproline Dipeptides
- • Non-natural Amino Acids
- • cGMP Manufactured
Long-Acting Side Chain Library
Comprehensive molecular block library for next-gen long-acting peptide drugs. Rapid screening and customization.
- • C12–C22 Aliphatic Chains
- • PEGylated Spacers
- • Biotin & Fluorescent Tags
- • Proprietary Design